msDNATM: a backbone-free,

linear, and high-fidelity DNA

minivector
 
 
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High-fidelity DNA minivector: In vivo E.coli-based production process incorporates intracellular DNA mismatch repair, leading to higher-fidelity msDNA. This ensures the production of various gene therapy products with superior quality and consistency.

Linear, minimal, backbone-free DNA minivector: msDNA's linear and minimal structure is free from unnecessary sequences. 

Non-immunogenic DNA minivector: The absence of prokaryotic sequences carrying pathogen-associated molecular patterns and minimal cytokine-stimulating profile makes msDNA non-immunogenic.